Osteoclast differentiation翻译
WebSep 6, 2005 · Osteoclasts are derived from myeloid lineage cells, and their differentiation is supported by various osteotropic factors, including the tumor necrosis factor (TNF) family member TNF-related activation-induced cytokine (TRANCE). Web目的探讨三羟异黄酮类药Genistein对破骨细胞性骨吸收的作用及其机制.方法1,25(OH)2D3诱导小鼠骨髓细胞形成破骨样细胞,分别加入0 mol/L、10-9 mol/L、10-8mol/L、10-7 mol/L、10-6 mol/L、10-5 mol/L Genistein,于培养3,5和8 d分别计数抗酒石酸酸性磷酸酶阳性细胞个数;于培养12 d利用图像分析系统对骨吸收陷窝的面积进行测
Osteoclast differentiation翻译
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WebFeb 18, 2024 · FSS has been reported to affect the cell morphology and gene expression of osteoclasts and to inhibit their differentiation without affecting their viability. 22,23,24 … WebMay 15, 2003 · Osteoclasts are specialized cells derived from the monocyte/macrophage haematopoietic lineage that develop and adhere to bone matrix, then secrete acid and …
WebAn osteoclast (from Ancient Greek ὀστέον (osteon) 'bone', and κλαστός (clastos) 'broken') is a type of bone cell that breaks down bone tissue.This function is critical in the maintenance, repair, and remodeling of bones of … WebA polypeptide inhibiting RANK, pharmaceutical composition comprising the same, method of inhibiting osteoclast differentiation, a method of treating or preventing a disease caused by differentiation or activation of osteoclast, nucleic acid encoding the polypeptide, vector comprising the nucleic acid and a host cell transformed with the vector [P].
WebThe differentiation of osteoclasts is dependent on a tumor necrosis factor (TNF) family cytokine, receptor activator of nuclear factor (NF)-kappaB ligand (RANKL), as well as macrophage colony-stimulating factor (M-CSF). Congenital lack of osteoclasts causes osteopetrosis, investigation of which has provided insights into the essential molecules ... WebDec 2, 2009 · In vitro osteoclast differentiation of MDBM and TMC16 cells. Both M-CSF and RANKL are essential factors for osteoclast differentiation. 9, 10 MDBM cells were cultured in the presence of M-CSF and sRANKL. After 2 days culture, the morphology of cells changed from spindle-shaped to round (Fig. 2B). After 3 days culture, some …
Web骨质疏松发病率,prevalence of osteoporosis,音标,读音,翻译,英文例句,英语词典 2)prevalence rate of osteoporosis 3)Diabetic osteoporosis Objective:To observe the effects of glucose on the differentiation of osteoclast derived from rat bone marrow cells,and to...
WebMay 15, 2003 · Osteoclasts are specialized cells derived from the monocyte/macrophage haematopoietic lineage that develop and adhere to bone matrix, then secrete acid and lytic enzymes that degrade it in a specialized, extracellular compartment. multer change filenameWebJul 25, 2024 · Osteoporosis is a common skeletal disease with marked bone loss, deterioration of the bone microstructure and bone fragility. An abnormal bone remodelling cycle with relatively increased bone resorption is the crucial pathophysiological mechanism. Bone remodelling is predominantly controlled by osteoblasts and osteoclasts, which are … multer check file typeWebOsteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion.Macrophage colony stimulating fac. 掌桥科研 一站式科研服务平台. 学术工具. 文档翻译; multer boundary not foundWebNov 30, 2024 · 破骨细胞 (英语: osteoclast )又称 蚀骨细胞 [1] ,是一种存在于 骨 组织中的细胞,由多个 单核细胞 融合而成,直径最大可达100微米, 细胞核 的数目一般是6-50个 [2] [3] 。 破骨细胞由核因子B配体激活受体(RANKL),以及巨噬细胞集落刺激因子(M-CSF)刺激分化产生。 它的主要功能是通过释放 乳酸 、 柠檬酸 、 碳酸 、碳酸酐酶及 … multer create folder if not existsWebOct 20, 2024 · The W9 peptide directly stimulates osteoblast differentiation via RANKL signaling. We reported previously that OPG-deficient mouse-derived osteoblasts strongly support osteoclast formation when co-cultured with OPG-deficient bone-marrow hemopoietic cells, even in the absence of bone-resorbing factors [].In contrast, when … multer check if file is emptyWebOsteoclasts are giant cells containing between 10 and 20 nuclei. They closely attach to the bone matrix by binding its surface integrins to a bone protein called vitronectin. This close apposition seals off an area of the bone beneath the osteoclast and allows the osteoclast to form a microenvironment that resorbs bone. how to measure a segmentWeb中文翻译 手机版. n. 1.破骨细胞。. 2.折骨器。. "lining osteoclast"中文翻译 覆盖型破骨细胞. "mononucleated osteoclast"中文翻译 单核破骨细胞. "like-osteoclast-activating factor" … multer check if file uploaded